Relation Between Chest CT Findings and Clinical Conditions of Coronavirus Disease (COVID-19) Pneumonia: A Multicenter Study by Zhao et al. - American Journal of Roentgenology
Bron: 19 February 2020: https://www.ajronline.org/doi/pdf/10.2214/AJR.20.22976
By Zhao et al.
To investigate the relation between chest CT findings and the clinical conditions of COVID-19 pneumonia
- Most COVID-19 patients have ground-glass opacities (GGO) or mixed GGO and consolidation and vascular enlargement in the lesion.
- Lesions are more likely to have peripheral multifocal distribution in bilateral lung regions, predominantly lower lung regions.
- Retrospective study in 4 hospitals in Hunan, China
- 101 patients: COVID-19 positive and CT-scan
- 55.4% male, age: 44 years (range 17-75)
- Epidemiology: direct exposure 83%, indirect exposure 12%, no exposure 5%
- Symptoms: fever 78%, cough 62%, myalgia/fatigue 17%, sore throat 12%
- Groups: Type according guideline on COVID-19 (trial version 5) issued by the China National Health Commission.
- non-emergency (mild- and common-type): 87 (48 men, 39 women)
- emergency (severe- and fatal-type): 14 (eight men, six women)
- CT-scan findings:
- Ground-glass opacities (GGO) 86.1%
- Mixed GGO and consolidation 64.4%
- Vascular enlargement in the lesion 71.3%
- Traction bronchiectasis 52.5%
- Architectural distortion 21.8%
- Pleural effusions 13.9%
- Peripheral 87.1%
- Bilateral lung regions 82.2%
- Lower lung predominant 54.5%
- Multifocal / Diffuse lesions 54.5% / 31.7%
- Emergency group:
- Older (53 vs 43 years, p < 0.05)
- CT: more traction bronchiectasis (85 vs 47%), architectural distortion (43 vs 18%), pleural effusions (35 vs 10%), diffuse lesions (79 vs 24%) (p < 0.05)
Non-emergency case. Left arrow: Traction bronchiectasis. Right arrow: Vascular enlargement
Emergency case. Arrow: bilateral diffuse ground-glass opacities and reticulation